Conclusion : mitral and aortic valves were vulnerable to calcification which was the major change of heart valve in patients with crf on maintenance hemodialysis, the degree of calcification was closely related to hyperphosphoremia, secondary hyperparathyroidism and a longer period of hemodialysis 结论:慢性肾功能衰竭维持性血液透析患者心脏瓣膜病变均以钙化为主,尤以二尖瓣、主动脉瓣易发,且钙化程度与钙磷乘积、继发性甲状旁腺机能亢进和血液透析年限密切相关。