- g蛋白即gtp结合蛋白
- gtp: GTP ＝ Guanosine triphosphate ...
- binding: adj. 1.缚[捆、绑]…的；黏合的；系连的，连结的。 ...
- gtp binding and hydrolyzing protein: gtp结合与水解蛋白,g蛋白
- gtp binding protein: gtp结合蛋白
- gtp: GTP ＝ Guanosine triphosphate 【化学】三磷酸鸟苷。
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gtp-binding中文什么意思
- g蛋白即gtp结合蛋白
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例句与用法
- Homologues of era have been identified in prokaryotes and eukaryotes . there are two domains in era : the n - terminal gtp - binding domain and c - terminal rna binding kh domain . era plays an important role in cell cycle progression at a specific point in the cycle , after chromosome partitioning but before cytokinesis
Era是在原核和真核生物以及植物中普遍存在的g蛋白，是一个结构上既具有gtp结合结构域又有rna结合结构域、不同于ras的独特的新的g蛋白亚家族。 - Rapl belongs to ras superfamily of small gtp - binding proteins , which is considered to control cell growth , differentiation and survival . rapl was regarded as an antagonist of ras because it can revert the phenotype of oncogene ras transformed cells . recent researches show that rapl has its ras - independent functions in a variety of cellular systems besides its effect as an antagonist of ras
Rap1除具有逆转原癌基因ras激活突变体所导致的细胞形态改变而被认为是ras的拮抗物外，最近的研究还发现rap1在一系列的细胞系统中有独立于ras之外的功能，如控制与细胞粘附有关的事件等，因而成为研究的热点。 - Rab7 mediates transport of proteins from early endosome to late endosome or fusion of early endosome with late endosome , while rab9 mediates the retransport of m6pr from late endosome to trans - golgi network . the gtp / gdp - binding ability and intrinsic gtpase activity of rab proteins make them exist in rab - gtp or rab - gdp status . the switching of rabs between gtp - bound ( active ) and gdp - bound ( inactive ) forms requires other regulatory proteins , including guanosine exchange factor ( gef ) , gdp dissociation inhibitor ( gdi ) and gtpase activating protein ( gap ) , and lays the foundations of rab function
Rab蛋白家族成员和其他小g蛋白一样可以结合gtp gdp ，在自身gtp酶的水解作用和其他蛋白( gef 、 gap 、 gdi )的调节作用下发生gtp (活化状态)和gdp (无活性)结合形式的转变；同时rab蛋白也在膜结合性( membrane - bound )和胞浆可溶性( cytosolic )之间变化，一个变化过程对应着一个功能循环，接着rab蛋白回到初始状态参与下一个循环。