Studies suggest that programmed cell death ( pcd; cells that occur pcd have a strict morphological change called apoptosis ) occurs after tbi 程序性细胞死亡(programmedcelldeath,pcd)参与了神经细胞损伤的发病机制。细胞进行pcd通常经过一个严格的形态学变化被称之为凋亡(apoptosis)。
For organs to form during embryonic development, some cells must commit suicide . without such programmed cell death, we would all be born with webbed feet, like ducks 对胚胎发育期间形成的器官来说,部分细胞必须自绝生路。如果没有这种程序化细胞死亡,我们生下来都会像鸭子一样有带蹼的脚。
What is more, we found that normal huntingtin appears to keep neurons alive by halting the cascade of molecular events that usually leads to apoptosis, or programmed cell death 我们更进一步发现,正常的杭丁顿蛋白似乎能够阻断导致细胞凋亡(计画中细胞死亡)的连锁分子反应,因而维持细胞的存活。
Experts know that cancers spread in two separate ways ? by the uncontrolled proliferation of cells, and by their refusal to undergo normal, healthy, programmed cell death, or " apoptosis . 专家们知道肿瘤发展有两种方式,通过不可控制的细胞增殖;通过它们拒绝进入正常的健康的程序性细胞死亡即凋亡。
Refers to programmed cell death is a form of cell death in which a programmed sequence of events leads to the destruction of cells without releasing harmful substances into the surrounding area 细胞程序性死亡是指细胞死亡的一种形式,它由程序次序控制导致细胞毁灭的现象的逐一发生,而不会对周遭环境释放有害物质。
The research is detailed in the may 13 issue of the journal carcinogenesis . follow-up research not published in the journal indicates a possible reason for the difference . exercise enhances a process called uvb-induced apoptosis, which means programmed cell death 科学家进行的深入研究向人们表述了之所以会出现这种差别的一个可能的原因,即体育锻炼增强了一个名为紫外线b诱发的细胞凋亡uvb-inducedapoptosis的过程,细胞凋亡是程序性细胞死亡
Labeling tunel method . the cell ultrastructural changes were similar to apoptosis in animal cells : the apical meristemetic cells underwent the programmed cell death . this was first detected in the apex cells of apical meristem, while peripheral cells differentiated gradually into different parts of a floral bud . but all the cells in the floral bud were subjected to the pcd process before it developed into a complete flower . 140bp dna fragment was found to deposit in apical bud during the plant development . the most important role of caspase-8 was detected by western blot, and the expression of the procaspase-8 was time-related with the dna frgmentation and the transformation from vegetative to the reproductive growth . these results suggested that pcd was an active process during the differentiation of apical meristem, and the senescence observed in the apical bud was due to the pcd process 显微超微结构研究表明,短日照条件下豌豆顶芽的衰老过程是从营养生长锥向花芽的转化,而用dna原位末端标记tunelcaspase-8westernblot和140bpdna片断积累的试验结果证明,转化为花芽的整个生长锥细胞发生了编程性死亡pcd,而且其最顶端部分细胞首先发生pcd,而顶端周围的分生组织细胞逐渐分化出花芽的各部分,但顶芽最后并没有发育成为完整的花,所有细胞就都发生pcd,从而顶芽衰老。
The paper summarizes research advances about the developments of somatic embryos in several conifers, which have appeared at home and abroad in recent years, mainly in the effects of medium components in tissue culture and aba on the development of somatic embryos, and cytology, programmed cell death, genes and protein composition related to the development of somatic embryos, and further discusses the developmental mechanisms of somatic embryos and the role of somatic embryos in genetic transformation system 本文综述了近年来国内外有关裸子植物中几种松杉类植物体细胞胚发育过程的研究报道,其中主要涉及培养基成分和脱落酸(aba)对体细胞胚发育的影响,以及体细胞胚发育在细胞学、细胞程序性死亡、相关基因和蛋白质组学等方面的研究进展,并进一步讨论了松杉类植物体细胞胚的发育机理,以及体细胞胚在遗传转化系统中的作用。
Al toxicity-induced ultraweak luminescence ( ul ), sister-chromatid exchanges ( sces ), programmed cell death ( pcd ) in root tips of barley, al-resistant genetic engineering and the role of root border cells in al toxicity were studied respectively, in order to explore some new pathways for al toxicity, al-resistant mechanism and genetic improvement 大麦是铝毒极为敏感的作物,本实验以大麦为材料,开展了铝毒诱导的根尖细胞超微弱发光、姐妹染色单体交换(sce)、细胞程序性死亡、耐铝基因工程及边缘细胞在铝毒中的功能研究。试图为植物铝毒及耐铝机制和遗传改良研究探索新途径。
The upr pathway in mammals links with several branches, including the increased transcription of a series of genes that encode folding-related proteins, the ubiquitous down-regulation of protein translation, programmed cell death mediated by chop and degradation of er-related proteins, etc . though somewhat independent, these branches do have multiple connections 哺乳动物细胞的upr通路涉及与折叠能力相关的一系列基因转录上调、蛋白质普启蒙翻译下降、ghop介导的程序性死亡及内质网相关性蛋白降解等多个分支。这些分支虽有一定的自主性,但却存在着千丝万缕的联系,因此其中某个支路上效应成分的改变,就可能会对整个upr通路产生影响,甚至影响细胞的命运。