Mrs . brown : yes . get me a lit - tle . it smells nice 布朗太太:好,给我来一点。闻起来真香。
Okay so you tellme whatyou think it sworth i d really like to set tle the claim 噢,那么你说,你认为它值多少?我确实很希望索赔得到解决。
May : exactly ! everyday is children ' s day . i feel a lit - tle bit jealous of children now 太对了!现在每天都是儿童节。我都有点嫉妒小孩子了!
Why would anyone put a ship in a bot - tle - it must be very difficult and take a long time 为什么要把船放到瓶子里去呢?这肯定非常艰难,而且要花费很长的时间!
[ size = 4 ] [ color = teal ] okay so you tellme whatyou think it sworth i d really like to set tle the claim 噢,那么你说,你认为它值多少?我确实很希望索赔得到解决。
On the other hand , the decrease of tle1 expression inhibited the proliferation of hela cells and induces some of the cells to die Tle的表达下降使宫颈癌细胞的增殖减慢并出现部分细胞死亡,对胃癌细胞则无明显影响。
These results indicated that aes might function as an antagonist of tle by binding with tle and inhibit the translocation of tle into nucleus 提示aes可能通过抑制tle进入胞核及形成四聚体而对tle的转录抑制功能起桔抗作用。
It has been reported that tle1 expression was up - regulated in cervix cancer cells and peptide derived from aes could be recognized by ctls from ovary cancer patients 有报道tle在宫颈癌组织中表达升高,而aes来源的肽段可被卵巢癌患者的l识别。
These results indicated that molecules of tle family might play a role in gp130 signaling . the amino - terminal regions of aes and tle are highly homologous , both contains q ( glutamine ) domain 已知tle可通过q结构域形成四聚体,而且四聚体的形成对tle发挥转录抑制功能来说是必需的。
To investigate the possible interaction between aes and the ubiquitously expressed tle molecule , tle1 , we constructed a serial of expression vectors containing various domains of aes and tle1 为确定人aes与tle分子问是否存在相互作用,我们通过r扩增,构建了含有编码s与ei分子不同结构域的。